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1

Antagonistic cytoprotective effects of C60 fullerene nanoparticles in simultaneous exposure to benzo[a]pyrene in a molluscan animal model

Moore, Michael N., Sforzini, Susanna, Viarengo, Aldo, Barranger, Audrey, Aminot, Yann, Readman, James W., Khlobystov, Andrei N., Arlt, Volker M., Banni, Mohamed, Jha, Awadhesh N.

Journal:

Science of The Total Environment

Year:

2021

File:

PDF, 3.97 MB

2021

2

Merging nano-genotoxicology with eco-genotoxicology: An integrated approach to determine interactive genotoxic and sub-lethal toxic effects of C60 fullerenes and fluoranthene in marine mussels, Mytilus sp.

Sherain N. Al-Subiai, Volker M. Arlt, Patricia E. Frickers, James W. Readman, Björn Stolpe, Jamie R. Lead, A. John Moody, Awadhesh N. Jha

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2012

Language:

english

File:

PDF, 1.29 MB

english, 2012

3

AHR- and DNA-Damage-Mediated Gene Expression Responses Induced by Benzo( a )pyrene in Human Cell Lines

Hockley, Sarah L., Arlt, Volker M., Brewer, Daniel, te Poele, Robert, Workman, Paul, Giddings, Ian, Phillips, David H.

Journal:

Chemical Research in Toxicology

Year:

2007

Language:

english

File:

PDF, 3.25 MB

english, 2007

4

Bacillus Calmette-Guerin therapy in non-muscle-invasive bladder carcinoma after renal transplantation for end-stage aristolochic acid nephropathy

Roumeguère, Thierry, Broeders, Nilufer, Jayaswal, Avinash, Rorive, Sandrine, Quackels, Thierry, Pozdzik, Agnieszka, Arlt, Volker M., Schmeiser, Heinz H., Nortier, Joëlle L.

Journal:

Transplant International

Year:

2015

Language:

english

File:

PDF, 302 KB

english, 2015

5

Tissue-specific in vivo genetic toxicity of nine polycyclic aromatic hydrocarbons assessed using the Muta™Mouse transgenic rodent assay

Long, Alexandra S., Lemieux, Christine L., Arlt, Volker M., White, Paul A.

Journal:

Toxicology and Applied Pharmacology

Year:

2016

Language:

english

File:

PDF, 1.08 MB

english, 2016

6

Genotoxicity of fine and coarse fraction ambient particulate matter in immortalised normal (TT1) and cancer-derived (A549) alveolar epithelial cells

Jarvis, Ian W.H., Enlo-Scott, Zachary, Nagy, Eszter, Mudway, Ian S., Tetley, Teresa D., Arlt, Volker M., Phillips, David H.

Journal:

Environmental and Molecular Mutagenesis

Year:

2018

Language:

english

File:

PDF, 522 KB

english, 2018

7

DNA adducts and mutagenic specificity of the ubiquitous environmental pollutant 3-nitrobenzanthrone in Muta Mouse

Volker M. Arlt, Li Zhan, Heinz H. Schmeiser, Masamitsu Honma, Makoto Hayashi, David H. Phillips, Takayoshi Suzuki

Journal:

Environmental and Molecular Mutagenesis

Year:

2004

Language:

english

File:

PDF, 156 KB

english, 2004

8

Mutagenic potential of nitrenium ions of nitrobenzanthrones: Correlation between theory and experiment

Jóhannes Reynisson, Marie Stiborová, Václav Martínek, Gonçalo Gamboa da Costa, David H. Phillips, Volker M. Arlt

Journal:

Environmental and Molecular Mutagenesis

Year:

2008

Language:

english

File:

PDF, 223 KB

english, 2008

9

The human carcinogen aristolochic acid i is activated to form DNA adducts by human NAD(P)H:quinone oxidoreductase without the contribution of acetyltransferases or sulfotransferases

Marie Stiborová, Jaroslav Mareîs, Eva Frei, Volker M. Arlt, Václav Martínek, Heinz H. Schmeiser

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 433 KB

english, 2011

10

Simultaneous measurement of benzo[a]pyrene-induced Pig-a and lacZ mutations, micronuclei and dna adducts in mutaTMmouse

Christine L. Lemieux, George R. Douglas, John Gingerich, Souk Phonethepswath, Dorothea K Torous, Stephen D. Dertinger, David H. Phillips, Volker M. Arlt, Paul A. White

Journal:

Environmental and Molecular Mutagenesis

Year:

2011

Language:

english

File:

PDF, 309 KB

english, 2011

11

Is aristolochic acid a risk factor for Balkan endemic nephropathy-associated urothelial cancer?

Volker M. Arlt, Dusan Ferluga, Marie Stiborova, Annie Pfohl-Leszkowicz, Mato Vukelic, Stjepan Ceovic, Heinz H. Schmeiser, Jean-Pierre Cosyns

Journal:

International Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 203 KB

english, 2002

12

Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells

Volker M. Arlt, Hansruedi Glatt, Eva Muckel, Ulrike Pabel, Bernd L. Sorg, Albrecht Seidel, Heinz Frank, Heinz H. Schmeiser, David H. Phillips

Journal:

International Journal of Cancer

Year:

2003

Language:

english

File:

PDF, 330 KB

english, 2003

13

DNA adduct formation by the ubiquitous environmental contaminant 3-nitrobenzanthrone in rats determined by 32P-postlabeling

Volker M. Arlt, Christian A. Bieler, Walter Mier, Manfred Wiessler, Heinz H. Schmeiser

Journal:

International Journal of Cancer

Year:

2001

Language:

english

File:

PDF, 138 KB

english, 2001

14

Aristolochic acid (AA)-DNA adduct as marker of AA exposure and risk factor for AA nephropathy-associated cancer

Volker M. Arlt, Véronique Alunni-Perret, Gérald Quatrehomme, Patrick Ohayon, Laetitia Albano, Hacène Gaïd, Jean-Francois Michiels, Alain Meyrier, Elisabeth Cassuto, Manfred Wiessler, Heinz H. Schmeise

Journal:

International Journal of Cancer

Year:

2004

Language:

english

File:

PDF, 112 KB

english, 2004

15

DNA adduct formation by the environmental contaminant 3-nitrobenzanthrone after intratracheal instillation in rats

Christian A. Bieler, Michael G. Cornelius, Reinhold Klein, Volker M. Arlt, Manfred Wiessler, David H. Phillips, Heinz H. Schmeiser

Journal:

International Journal of Cancer

Year:

2005

Language:

english

File:

PDF, 186 KB

english, 2005

16

Identification of three major DNA adducts formed by the carcinogenic air pollutant 3-nitrobenzanthrone in rat lung at the C8 and N2 position of guanine and at the N6 position of adenine

Volker M. Arlt, Heinz H. Schmeiser, Martin R. Osborne, Masanobu Kawanishi, Takaharu Kanno, Takashi Yagi, David H. Phillips, Takeji Takamura-Enya

Journal:

International Journal of Cancer

Year:

2006

Language:

english

File:

PDF, 483 KB

english, 2006

17

TP53 mutation signature supports involvement of aristolochic acid in the aetiology of endemic nephropathy-associated tumours

Tatiana Nedelko, Volker M. Arlt, David H. Phillips, Monica Hollstein

Journal:

International Journal of Cancer

Year:

2009

Language:

english

File:

PDF, 122 KB

english, 2009

18

Gene expression changes induced by the human carcinogen aristolochic acid I in renal and hepatic tissue of mice

Volker M. Arlt, Jie Zuo, Kristina Trenz, Candice A. Roufosse, Graham M. Lord, Joelle L. Nortier, Heinz H. Schmeiser, Monica Hollstein, David H. Phillips

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1002 KB

english, 2011

19

Aryl hydrocarbon receptor activation during pregnancy, and in adult nulliparous mice, delays the subsequent development of DMBA-induced mammary tumors

Tao Wang, Heather M. Gavin, Volker M. Arlt, B. Paige Lawrence, Suzanne E. Fenton, Daniel Medina, Beth A. Vorderstrasse

Journal:

International Journal of Cancer

Year:

2011

Language:

english

File:

PDF, 1.62 MB

english, 2011

20

Detection and quantitation of N-(deoxyguanosin-8-yl)-2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine adducts in DNA using online column-switching liquid chromatography tandem mass spectrometry

Rajinder Singh, Volker M. Arlt, Colin J. Henderson, David H. Phillips, Peter B. Farmer, Gonçalo Gamboa da Costa

Journal:

Journal of Chromatography B

Year:

2010

Language:

english

File:

PDF, 315 KB

english, 2010

21

Effects of nitrated-polycyclic aromatic hydrocarbons and diesel exhaust particle extracts on cell signalling related to apoptosis: Possible implications for their mutagenic and carcinogenic effects

Nina E. Landvik, Morgane Gorria, Volker M. Arlt, Nana Asare, Anita Solhaug, Dominique Lagadic-Gossmann, Jørn A. Holme

Journal:

Year:

2007

Language:

english

File:

PDF, 1.44 MB

english, 2007

22

The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicity

Marie Stiborová, Helena Dračínská, Jana Mizerovská, Eva Frei, Heinz H. Schmeiser, Jiří Hudeček, Petr Hodek, David H. Phillips, Volker M. Arlt

Journal:

Year:

2008

Language:

english

File:

PDF, 918 KB

english, 2008

23

Aristolochic acid impedes endocytosis and induces DNA adducts in proximal tubule cells

Lebeau, Catherine, Arlt, Volker M., Schmeiser, Heinz H., Boom, Alain, Verroust, Pierre J., Devuyst, Olivier, Beauwens, Renaud

Journal:

Kidney International

Year:

2001

File:

PDF, 2.40 MB

2001

24

Aristolochic acid nephropathy and the peritoneum: Functional, structural, and molecular studies

Gillerot, Gaelle, Goffin, Eric, Moulin, Pierre, Arlt, Volker M., Phillips, David H., Cosyns, Jean-Pierre, Devuyst, Olivier

Journal:

Kidney International

Year:

2003

Language:

english

File:

PDF, 2.91 MB

english, 2003

25

Influence of cell cycle on responses of MCF-7 cells to benzo[a]pyrene

Hamza Hamouchene, Volker M Arlt, Ian Giddings, David H Phillips

Journal:

Year:

2011

Language:

english

File:

PDF, 1.63 MB

english, 2011

26

Constitutive expression of bioactivating enzymes in normal human prostate suggests a capability to activate pro-carcinogens to DNA-damaging metabolites

Francis L. Martin, Imran I. Patel, Osman Sozeri, Paras B. Singh, Narasimhan Ragavan, Caroline M. Nicholson, Eva Frei, Walter Meinl, Hansruedi Glatt, David H. Phillips, Volker M. Arlt

Journal:

Year:

2010

Language:

english

File:

PDF, 341 KB

english, 2010

27

Effects of dexfenfluramine on aristolochic acid nephrotoxicity in a rat model for Chinese-herb nephropathy

Frédéric Debelle, Joëlle Nortier, Volker M. Arlt, Eric De Prez, Anne Vienne, Isabelle Salmon, David H. Phillips, Monique Deschodt-Lanckman, Jean-Louis Vanherweghem

Journal:

Archives of Toxicology

Year:

2003

Language:

english

File:

PDF, 520 KB

english, 2003

28

Molecular evidence for an involvement of organic anion transporters (OATs) in aristolochic acid nephropathy

Nadiya Bakhiya, Volker M. Arlt, Andrew Bahn, Gerhard Burckhardt, David H. Phillips, Hansruedi Glatt

Journal:

Year:

2009

Language:

english

File:

PDF, 505 KB

english, 2009

29

Linking environmental carcinogen exposure to TP53 mutations in human tumours using the human TP53 knock-in (Hupki) mouse model

Jill E. Kucab, David H. Phillips, Volker M. Arlt

Journal:

Year:

2010

Language:

english

File:

PDF, 503 KB

english, 2010

30

The 32P-postlabeling assay for DNA adducts

Phillips, David H, Arlt, Volker M

Journal:

Nature Protocols

Year:

2007

Language:

english

File:

PDF, 450 KB

english, 2007

31

Metabolic activation of diesel exhaust carcinogens in primary and immortalized human TP53 knock-in (Hupki) mouse embryo fibroblasts

Jill E. Kucab, David H. Phillips, Volker M. Arlt

Journal:

Environmental and Molecular Mutagenesis

Year:

2012

Language:

english

File:

PDF, 1.21 MB

english, 2012

32

Mutagenicity and DNA adduct formation by aristolochic acid in the spleen of Big Blue® rats

L. Patrice McDaniel, Elizabeth R. Elander, Xiaoqing Guo, Tao Chen, Volker M. Arlt, Nan Mei

Journal:

Environmental and Molecular Mutagenesis

Year:

2012

Language:

english

File:

PDF, 790 KB

english, 2012

33

ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues

Yiying Wang, Volker M. Arlt, Candice A. Roufosse, Karen L. McKim, Meagan B. Myers, David H. Phillips, Barbara L. Parsons

Journal:

Environmental and Molecular Mutagenesis

Year:

2012

Language:

english

File:

PDF, 693 KB

english, 2012

34

Different mechanisms involved in apoptosis following exposure to benzo[a]pyrene in F258 and Hepa1c1c7 cells

Jørn A. Holme, Morgane Gorria, Volker M. Arlt, Steinar Øvrebø, Anita Solhaug, Xavier Tekpli, Nina E. Landvik, Laurence Huc, Olivier Fardel, Dominique Lagadic-Gossmann

Journal:

Chemico-Biological Interactions

Year:

2007

Language:

english

File:

PDF, 1.28 MB

english, 2007

35

DNA adduct formation and mutation induction by aristolochic acid in rat kidney and liver

Nan Mei, Volker M. Arlt, David H. Phillips, Robert H. Heflich, Tao Chen

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2006

Language:

english

File:

PDF, 312 KB

english, 2006

36

Whole body exposure of mice to secondhand smoke induces dose-dependent and persistent promutagenic DNA adducts in the lung

Sang-In Kim, Volker M. Arlt, Jae-In Yoon, Kathleen J. Cole, Gerd P. Pfeifer, David H. Phillips, Ahmad Besaratinia

Journal:

Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis

Year:

2011

Language:

english

File:

PDF, 784 KB

english, 2011

37

Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: Studies with the hepatic NADPH:Cytochrome P450 reductase null mouse

Marie Stiborová, Volker M. Arlt, Colin J. Henderson, C. Roland Wolf, Věra Kotrbová, Michaela Moserová, Jiří Hudeček, David H. Phillips, Eva Frei

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 458 KB

english, 2008

38

Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53

Maria L. Simões, Sarah L. Hockley, Tanja Schwerdtle, Gonçalo Gamboa da Costa, Heinz H. Schmeiser, David H. Phillips, Volker M. Arlt

Journal:

Toxicology and Applied Pharmacology

Year:

2008

Language:

english

File:

PDF, 1.29 MB

english, 2008

39

Covalent binding of the anticancer drug ellipticine to DNA in V79 cells transfected with human cytochrome P450 enzymes

Eva Frei, Christian A Bieler, Volker M Arlt, Manfred Wiessler, Marie Stiborová

Journal:

Biochemical Pharmacology

Year:

2002

Language:

english

File:

PDF, 165 KB

english, 2002

40

Aristolochic acid nephropathy in a Chinese patient: Time to abandon the term “Chinese herbs nephropathy”?

Gaëlle Gillerot, Michel Jadoul, Volker M. Arlt, Charles van Ypersele de Strihou, Heinz H. Schmeiser, Paul P.H. But, Christian A. Bieler, Jean-Pierre Cosyns

Journal:

American Journal of Kidney Diseases

Year:

2001

Language:

english

File:

PDF, 63 KB

english, 2001

41

DNA adducts and p53 mutations in a patient with aristolochic acid-associated nephropathy

Graham M. Lord, Monica Hollstein, Volker M. Arlt, Candice Roufosse, Charles D. Pusey, Terry Cook, Heinz H. Schmeiser

Journal:

American Journal of Kidney Diseases

Year:

2004

Language:

english

File:

PDF, 355 KB

english, 2004

42

Detection of Herba Aristolochia Mollissemae in a patient with unexplained nephropathy

Stanley H. Lo, Kin-shing Wong, Volker M. Arlt, David H. Phillips, Chi-kong Lai, Wing-tat Poon, Ching-kit Chan, Ka-leung Mo, Kwok-wah Chan, Albert Chan

Journal:

American Journal of Kidney Diseases

Year:

2005

Language:

english

File:

PDF, 172 KB

english, 2005

43

Time- and concentration-dependent changes in gene expression induced by benzo(a)pyrene in two human cell lines, MCF-7 and HepG2

Sarah L Hockley, Volker M Arlt, Daniel Brewer, Ian Giddings, David H Phillips

Journal:

Year:

2006

Language:

english

File:

PDF, 908 KB

english, 2006

44

Evidence of exposure to aristolochic acid in patients with urothelial cancer from a Balkan endemic nephropathy region of Romania

Heinz H. Schmeiser, Jill E. Kucab, Volker M. Arlt, David H. Phillips, Monica Hollstein, Gheorghe Gluhovschi, Cristina Gluhovschi, Mirela Modilca, Liviu Daminescu, Ligia Petrica, Silvia Velciov

Journal:

Environmental and Molecular Mutagenesis

Year:

2012

Language:

english

File:

PDF, 169 KB

english, 2012

45

Bioactivation of 3-aminobenzanthrone, a human metabolite of the environmental pollutant 3-nitrobenzanthrone: evidence for DNA adduct formation mediated by cytochrome P450 enzymes and peroxidases

Volker M. Arlt, Colin J. Henderson, C. Roland Wolf, Heinz H. Schmeiser, David H. Phillips, Marie Stiborova

Journal:

Year:

2006

Language:

english

File:

PDF, 728 KB

english, 2006

46

The influence of diesel exhaust on polycyclic aromatic hydrocarbon-induced DNA damage, gene expression, and tumor initiation in Sencar mice in vivo

Lauren A. Courter, Andreas Luch, Tamara Musafia-Jeknic, Volker M. Arlt, Kay Fischer, Robert Bildfell, Cliff Pereira, David H. Phillips, Miriam C. Poirier, William M. Baird

Journal:

Year:

2008

Language:

english

File:

PDF, 306 KB

english, 2008

47

The genotoxic air pollutant 3-nitrobenzanthrone and its reactive metabolite N-hydroxy-3-aminobenzanthrone lack initiating and complete carcinogenic activity in NMRI mouse skin

Heinz H. Schmeiser, Gerhard Fürstenberger, Takeji Takamura-Enya, David H. Phillips, Volker M. Arlt

Journal:

Year:

2009

Language:

english

File:

PDF, 667 KB

english, 2009

48

DNA adduct formation in human hepatoma cells treated with 3-nitrobenzanthrone: analysis by the 32P-postlabeling method

Takaharu Kanno, Masanobu Kawanishi, Takeji Takamura-Enya, Volker M. Arlt, David H. Phillips, Takashi Yagi

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2007

Language:

english

File:

PDF, 554 KB

english, 2007

49

3-Aminobenzanthrone, a human metabolite of the carcinogenic environmental pollutant 3-nitrobenzanthrone, induces biotransformation enzymes in rat kidney and lung

Marie Stiborová, Helena Dračínská, Markéta Martínková, Jana Mizerovská, Jiří Hudeček, Petr Hodek, Jiří Liberda, Eva Frei, Heinz H. Schmeiser, David H. Phillips, Volker M. Arlt

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2009

Language:

english

File:

PDF, 722 KB

english, 2009

50

Induction of biotransformation enzymes by the carcinogenic air-pollutant 3-nitrobenzanthrone in liver, kidney and lung, after intra-tracheal instillation in rats

Jana Mizerovská, Helena Dračínská, Eva Frei, Heinz H. Schmeiser, Volker M. Arlt, Marie Stiborová

Journal:

Mutation Research/Genetic Toxicology and Environmental Mutagenesis

Year:

2011

Language:

english

File:

PDF, 552 KB

english, 2011